https://drive.google.com/file/d/151Dv-IChW82N6wME6QS7-XmFSOQSMwLv/view?usp=share_link
Pathophysiology & Pathogenesis of Myocardial Infarction (MI).Professor Ali Altimimi
Myocardial Infarction MI, also known as “heart attack,”is the death of cardiac muscle (coagulative necrosis) resulting from ischemia. MI: commonly affected coronary vessel in persons with right dominant
coronary artery heart(90%of population). Left anterior descending artery(40-50%): it supplies the anterior left ventricle, apex and anterior two thirds of interventricular septum.
Right coronary artery(30-40%): it supplies the posterior wall of the left ventricle, posterior one third of interventricular septum.
Left circumflex artery(about 20%): it supplies the lateral wall of left ventricle.
Pathogenesis of MI.
– Most common cause is thrombosis on a preexisting disrupted atherosclerotic plaque.